Cancer BiologybioRxivPreprint
Decoupling nucleolar stress from DNA-damage in HCT116 colon cancer cells by targeting the interaction between ribosomal assembly factors Bop1/WDR12
This study shows that disrupting the Bop1-WDR12 interaction in HCT116 cells causes nucleolar stress and apoptosis without DNA damage, suggesting a non-genotoxic cancer therapy approach.
DOI 10.64898/2026.03.11.711022