BioinformaticsbioRxivPreprint
PFM: perturbed flow matching for structure-based drug design
Yankai Yu, Guikun Xu, Zhuyang Xie…·Li K
PFM generates 3D molecules that bind to protein targets with competitive structures and SOTA binding affinities, while significantly accelerating the generation process.
DOI 10.64898/2026.07.11.737913