Author

Zhuyang Xie

Sichuan Agricultural UniversityORCID 0000-0003-4587-2198Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

Guikun XuiD· 1 shared Li KiD· 1 shared Xiaobo Zhou· 1 shared Yankai YuiD· 1 shared Yi JiangiD· 1 shared Yi YangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBioinformatics

Guikun XuORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintJul 17, 2026

PFM: perturbed flow matching for structure-based drug design

Yankai Yu, Guikun Xu, Zhuyang Xie…·Li K

PFM generates 3D molecules that bind to protein targets with competitive structures and SOTA binding affinities, while significantly accelerating the generation process.

DOI 10.64898/2026.07.11.737913

protein structuredeep learning

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