Stevan Novakovic

A patient with Fanconi anemia developed triploid hematopoietic stem cells that lacked the disease phenotype, enabling sustained hematopoiesis through restored DNA repair.

This paper uses snATAC-seq to identify meiotic crossovers in sperm, revealing their distribution and molecular features in wildtype and Fancm-deficient mice.

This study shows Fancm deficiency increases crossover frequencies and disrupts gametogenesis in mice, with potential implications for human genomic instability disorders.