Ruijie Liu

This paper uses snATAC-seq to identify meiotic crossovers in sperm, revealing their distribution and molecular features in wildtype and Fancm-deficient mice.

This paper introduces sgcocaller and comapr, tools for haplotype assembly and crossover map analysis from single-gamete sequencing data, showing improved accuracy and efficiency over existing methods.

This study shows Fancm deficiency increases crossover frequencies and disrupts gametogenesis in mice, with potential implications for human genomic instability disorders.

The paper presents haplotype-resolved cattle genomes to identify structural variants and adaptation traits, finding expanded immune-related gene families and a fatty acid desaturase copy under positive selection in indicine cattle.