CHRFAM7A overexpression in human iPSC-derived Interneurons dysregulates α7-nAChR surface expression and alters response to oligomeric β-amyloid peptide
Maria Llach Pou, Camille Thiberge, Stéphanie Pons, Uwe Maskos, Isabelle Cloëz-Tayarani
This study shows that overexpression of CHRFAM7A in human iPSC-derived interneurons reduces surface α7-nAChR and alters ROS response to Aβ1-42.
bioRxiv · Jun 4, 2024 · PreprintNeuroscience