Maria Llach Pou

This study shows that overexpression of CHRFAM7A in human iPSC-derived interneurons reduces surface α7-nAChR and alters ROS response to Aβ1-42.

This study shows that TrkB activation in PV+ interneurons is essential for antidepressant-induced behavioral flexibility and synaptic plasticity in spatial and fear memory.

The paper uses optogenetics to activate TrkB receptors in the ventral hippocampus, enhancing plasticity and improving fear extinction in mice.

The paper shows that optogenetic activation of TrkB receptors in PV interneurons increases cortical plasticity by altering neuronal excitability and gene expression.