IFNγ protects motor neurons from oxidative stress via enhanced global protein synthesis in FUS-associated Amyotrophic Lateral Sclerosis
Amanda F. Assoni, Erika N. Guerrero, René Wardenaar, Danyllo Oliveira, Petra L. Bakker, Luciana Moura Alves, Valdemir Melechco Carvalho, Oswaldo Keith Okamoto, Mayana Zatz, Floris Foijer
This study shows that IFNγ treatment reduces apoptosis and improves translation rates in ALS6 patient-derived motor neurons under oxidative stress.
Brain Pathology · Aug 15, 2023Peer-reviewedNeuroscience