Author

Valdemir Melechco Carvalho

Fleury S.A. (Brazil)ORCID 0000-0002-9816-8615Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Mayana ZatziD· 2 shared Amanda F. AssoniiD· 1 shared Danyllo OliveiraiD· 1 shared Daria PanchenkoiD· 1 shared Elia Tamaso Espin Garcia CaldiniiD· 1 shared Erika N. GuerreroiD· 1 shared Ernesto GoulartiD· 1 shared Fernanda Chianca· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

Mayana ZatzORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJun 17, 2025

FOXM1 Inhibition Promotes Polyploidization and Metabolic Maturation in Human iPSC-Derived Hepatocytes by Modulating the Wnt/β-Catenin Pathway

Kayque Alves Telles-Silva, Lara Varela Bastos Pacheco, Sabrina Komatsu…·Mayana Zatz

This study shows that FOXM1 inhibition promotes terminal differentiation of human iPSC-derived hepatocytes by enhancing polyploidization and metabolic maturation through the Wnt/β-catenin pathway.

DOI 10.1101/2025.06.17.660221

humanbulk RNA-seq

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NeuroscienceBrain PathologyPeer-reviewedAug 15, 2023

IFNγ protects motor neurons from oxidative stress via enhanced global protein synthesis in FUS-associated Amyotrophic Lateral Sclerosis

Amanda F. Assoni, Erika N. Guerrero, René Wardenaar…·Floris Foijer

This study shows that IFNγ treatment reduces apoptosis and improves translation rates in ALS6 patient-derived motor neurons under oxidative stress.

9 citations

humanbulk RNA-seq

𝕏 PostBluesky