Author

Kunal Gupta

Medical College of WisconsinORCID 0000-0002-9847-0099Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Assay:electronic health records· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Hernan Gonzalo ReyiD· 2 shared Sean M. LewiD· 2 shared Sunil MathewiD· 2 shared Alexander Betancourt· 1 shared Amol P. YadaviD· 1 shared Ana Sofia Dominguez Zesati· 1 shared Benjamin W. ReesiD· 1 shared Connor Hauder· 1 shared

Activity by Year

2019-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersNeuroscience

Hernan Gonzalo ReyORCID

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Wnt activation prevents epileptogenic hippocampal remodeling in animal models of unilateral and bilateral temporal lobe epilepsy

Cora Helton, Nicole Rodgers, Kunal Gupta

This study shows that Wnt activation reduces epileptogenic hippocampal remodeling in TLE models by restoring Wnt signaling in immature dentate granule cells.

bioRxiv · May 10, 2026 · PreprintNeuroscience

Closed-loop spinal cord stimulation is superior in restoring locomotion in rodent models of Parkinson's Disease

Jacob C. Slack, Benjamin W. Rees, Eleonora Borda, Jonah Slack, Miguel A. L. Nicolelis, Sarah Elizabeth Zauber, Kunal Gupta, Amol P. Yadav

This study shows that closed-loop spinal cord stimulation (CLDCS) is more effective than traditional methods in restoring locomotion in a Parkinson's disease rodent model by targeting beta oscillations.

Brain stimulation · Aug 5, 2025Peer-reviewedNeuroscience

MCWs (MiCroWire sorter): A new framework for automated and reliable spike sorting in human intracerebral recordings.

Alexander Betancourt, Masoud Khani, Tapasi Brahma, Fernando Julian Chaure, Connor Hauder, Sunil Mathew, Ana Sofia Dominguez Zesati, Sean M. Lew, Kunal Gupta, Hernan Gonzalo Rey

MCWs provides an automated, open-source spike sorting pipeline for human intracerebral recordings, improving accuracy and reliability in single-neuron detection.

bioRxiv · Jul 9, 2025 · PreprintNeuroscience

An online dynamic experimental framework to study single neuron responses in humans

Sunil Mathew, Sofia Dominguez Zesati, Sean M. Lew, Kunal Gupta, Hernan Gonzalo Rey

This paper introduces an online framework for real-time single neuron data analysis and dynamic stimulus sampling in human epilepsy patients.

bioRxiv · Jul 7, 2025 · PreprintNeuroscience

Transcriptome profiling implicates a role for Wnt signaling during epileptogenesis in a mouse model of temporal lobe epilepsy

Muriel D. Mardones, Kunal Gupta

This study identifies dynamic transcriptional changes in the hippocampal dentate gyrus of a mouse model of temporal lobe epilepsy, highlighting dysregulation of the Wnt signaling pathway during the latent period of epileptogenesis.

bioRxiv · Jul 22, 2022 · PreprintNeuroscience

Post-ictal neuronal network remodeling and Wnt pathway dysregulation in the intra-hippocampal kainate mouse model of temporal lobe epilepsy

Kunal Gupta, Eric Schnell

The paper examines Wnt pathway dysregulation and neurogenesis changes in a mouse model of temporal lobe epilepsy following seizures.

PLoS ONE · Oct 9, 2019Peer-reviewedNeuroscience