Eric Schnell

This study shows that adult-born granule cells in the hippocampus have reduced parvalbumin interneuron-mediated inhibition after traumatic brain injury, while mature granule cells do not show this deficit.

This study shows that α2δ-2 is essential for synaptic inhibition in hippocampal parvalbumin-expressing interneurons, with its absence leading to increased excitation and seizure-like activity.

This study shows that loss of hilar mossy cells alters dentate gyrus structure and function, but the circuit remains functionally resilient.

The paper shows that exercise preferentially activates dentate granule cells via inputs from the lateral entorhinal cortex, not through dendritic molecular changes.

This study shows that Dystroglycan's extracellular and intracellular domains have distinct roles in inhibitory synapse formation and maintenance in cerebellar Purkinje cells.

This study examines hippocampal activation and histopathological changes in CACNA2D2 knockout mice, finding altered functional activity without significant structural changes associated with seizure susceptibility.

This study examines inhibitory synapse defects and seizure susceptibility in mouse models of dystroglycanopathy, showing that severe forms exhibit impaired CCK+/CB1R+ interneuron development and synaptic function.

This study investigates how mossy cells in the hippocampus reorganize their connectivity and function after status epilepticus, showing increased inhibitory effects despite reduced excitation.

This study shows that α2δ-2 is essential for coupling calcium entry to two postsynaptic signals in Purkinje cells.

This study examines the role of α2δ-2 protein in cerebellar climbing fiber synapses using Cacna2d2 knockout mice, revealing structural and functional changes in synaptic transmission and their impact on ataxia.

The paper examines Wnt pathway dysregulation and neurogenesis changes in a mouse model of temporal lobe epilepsy following seizures.

Exercise increases hippocampal synaptic function through activity-dependent expression of Mtss1L, a BAR protein that promotes dendritic spine formation.

The paper shows that sprouted mossy fibers in temporal lobe epilepsy can initiate recurrent network activity despite short-term depression due to high initial glutamate release and lack of adenosine inhibition.