Adam Buckle

The paper identifies TOP2B as a regulator of genome-nuclear lamina interactions, showing its role in partitioning genomic regions between the nuclear lamina and interior, with LBR playing a complementary role.

The paper investigates the chromatin structure changes during human centromere formation, finding that it involves active transcription and open chromatin, while surrounding regions become repressed and compact.

The paper introduces capC-MAP, a software package for analyzing Capture-C data, and benchmarks it against another package for similar data.

The paper develops a polymer model to predict 3-D chromatin folding using epigenetic and structural data, validated on gene loci across cell types.