Author

João T. Proença

Gulbenkian Institute for Molecular MedicineORCID 0000-0002-9861-8241Unclaimed ORCID profile · follow to get notified of new preprints

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Andre Lemos CarneiroiD· 1 shared Ehsan ValiollahiiD· 1 shared Vasco M. BarretoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperSynthetic Biology

Andre Lemos CarneiroORCID

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1 paper

Recent·Most cited

Synthetic BiologybioRxivPreprintMay 23, 2026

Endogenous intronic RNA tightly controls Cas9/CRISPR-mediated gene editing in human cells

Andre Lemos Carneiro, João T. Proença, Ehsan Valiollahi, Vasco M. Barreto

The paper introduces intcgRNA, a conditional guide RNA that uses endogenous intronic RNA to control CRISPR/Cas9 editing, showing improved specificity in human cells.

DOI 10.64898/2026.03.24.714022

humanCRISPR screen

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