Author

Grétar Tryggvason

ORCID 0000-0002-9884-8901Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

Jennifer M. KavraniD· 1 shared Katherine W. TrippiD· 1 shared Kyler A. Weingartner· 1 shared Rachel GreeniD· 1 shared Samuel BotterbuschiD· 1 shared Vienna L. HusoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

Jennifer M. KavranORCID

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1 paper

Recent·Most cited

A conserved dimerization element is required for protein kinase activation by trans-autophosphorylation

Samuel Botterbusch, Vienna L. Huso, Kyler A. Weingartner, Grétar Tryggvason, Katherine W. Tripp, Rachel Green, Jennifer M. Kavran

This study identifies a conserved helix (G) mediating dimerization during trans-autophosphorylation in kinases across species, showing it is required for activation despite structural diversity.

bioRxiv · May 25, 2026 · PreprintBiochemistry