Author

Zhen Zhang

Shanghai Jiao Tong UniversityORCID 0000-0002-9898-054XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Zhen Zhang6 papers · Baylor College of Medicine

Biology Disciplines

Click to filter author papers

Developmental Biology· 2 Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 4 Assay:bulk RNA-seq· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Beibei XuiD· 2 shared Kai DingiD· 2 shared Xin Shen· 2 shared Xiwen Jia· 2 shared Xudong CaoiD· 2 shared Yahui Liu· 2 shared Yulong HeiD· 2 shared Bo WangiD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersDevelopmental Biology

Beibei XuORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Endocardial TIE1 synergizes with TIE2 to regulate the atrial internal muscular network assembly

Kai Ding, Beibei Xu, Xinhao Yu, Xiwen Jia, Taotao Li, Xin Shen, Junda Li, Xudong Cao, Yahui Liu, Zhen Zhang, Yulong He

This study shows TIE1 and TIE2 work together in atrial development, with TIE1 specifically needed for atrial muscular network formation.

bioRxiv · Sep 3, 2026 · PreprintDevelopmental Biology

Lymphatics unload VEGFR3 in response to the alteration of VEGFR2-mediated transcriptional programs

T J Li, Xudong Cao, Fei Zhou, X G Li, W X, Xiuyan Zhang, H Zhong, Beibei Xu, Man Chu, Xiwen Jia, Kai Ding, Xin Shen, Yahui Liu, Yun Zhao, Zhen Zhang, , Yulong He

This study shows that VEGFR2 is essential for maintaining lymphatic endothelial identity and its loss alters transcriptional programs, reducing VEGFR3-mediated lymphangiogenesis.

Angiogenesis · Jul 26, 2026Peer-reviewedDevelopmental Biology

SORBS2 is a genetic factor contributing to cardiac malformation of 4q deletion syndrome

Fei Liang, Bo Wang, Juan Geng, Guoling You, Jingjing Fa, Min Zhang, Hunying Sun, Huiwen Chen, Qihua Fu, Xiaoqing Zhang, Zhen Zhang

The paper identifies SORBS2 as a genetic factor contributing to cardiac malformations in 4q deletion syndrome through dual roles in sarcomere integrity and second heart field progenitor fate.

eLife · Jun 7, 2021Peer-reviewedGenetics

Mathematical modelling of molecular heterogeneity identifies novel markers and subpopulations in complex tumors

Lulu Chen, Niya Wang, Robert C. Clarke, Zhen Zhang, Yue Wang

The paper develops an unsupervised method to identify marker genes and subpopulations in tumors without prior knowledge of marker genes or subpopulation composition.

bioRxiv · Mar 17, 2018 · PreprintBioinformatics