Beibei Xu

This study identifies TIE2-mediated positive feedback involving COUPTFII and VEGFR3 as essential for bone marrow sinusoid specification.

This study shows TIE1 and TIE2 work together in atrial development, with TIE1 specifically needed for atrial muscular network formation.

This study shows that endothelial ANGPT2 deficiency causes retinal vascular defects similar to retinopathy of prematurity, with impaired tip cell invasion and hypoxia-driven changes.

This study shows that VEGFR2 is essential for maintaining lymphatic endothelial identity and its loss alters transcriptional programs, reducing VEGFR3-mediated lymphangiogenesis.

This study investigates the role of TIE1 and its interaction with TIE2 in venous development, finding that TIE1 restricts angiogenic sprouting to coordinate vein formation.