Author

J. David Schnettler

University of CambridgeORCID 0000-0002-9909-6190Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Assay:metagenomics· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

E.C. CampbelliD· 1 shared Florian HollfelderiD· 1 shared Oskar James KleiniD· 1 shared Rashid KhashieviD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

E.C. CampbellORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintOct 30, 2025

A portable dynamic loop module enables phosphotriesterase function in cysteine-dependent hydrolases

J. David Schnettler, E.C. Campbell, Rashid Khashiev…·Florian Hollfelder

The paper identifies a novel phosphotriesterase from the DLH family and shows that loop flexibility influences activity, enabling engineering of higher activity in a human enzyme.

1 citation

metagenomicsexperimental assay

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