Cryo-electron microscopy reveals a single domain antibody with a unique binding epitope on fibroblast activation protein alpha
Zhen Xu, Akesh Sinha, Darpan N. Pandya, Nicholas Schnicker, Thaddeus J. Wadas
The paper reports the cryo-EM structure of a single domain antibody bound to FAP, revealing a unique epitope and describing affinity improvements through CDR3 mutations.
RSC Chemical Biology · Jan 1, 2025Peer-reviewedBiochemistry