Sahla Syed

Modulation of protein-DNA binding reveals mechanisms of spatiotemporal gene control in early Drosophila embryos

The paper investigates how multiple TF binding sites modulate enhancer activity in Drosophila embryos, showing that cooperative binding increases transcriptional output and affects promoter dynamics.

The nuclear to cytoplasmic ratio directly regulates zygotic transcription in Drosophila through multiple modalities

This study shows that the nuclear to cytoplasmic ratio regulates zygotic transcription in Drosophila through multiple mechanisms, independent of cell cycle length.