Amanda A. Amodeo

This study shows that H2A.Z levels act as a timer for the maternal-zygotic transition in Drosophila and zebrafish, influencing developmental timing through both nuclear and non-nuclear mechanisms.

This study shows NASP prevents H3 aggregation in the cytoplasm, indirectly protecting H3 from degradation during early Drosophila embryogenesis.

The paper investigates how the nuclear to cytoplasmic ratio influences H3.3 incorporation during zygotic genome activation in Drosophila by analyzing cell cycle state and chaperone binding.

The paper visualizes nuclear morphology and transport machinery in Drosophila during development, finding dynamic changes in NPC abundance and transport receptor puncta.

Bellymount-Pulsed Tracking enables continuous, non-invasive live imaging of Drosophila oogenesis for up to 16 hours by incorporating pulsed anesthesia and feeding periods.

The paper identifies that differential nuclear import timing controls gene expression onset in early embryonic development by regulating protein access to the genome.

This study shows that the nuclear to cytoplasmic ratio regulates zygotic transcription in Drosophila through multiple mechanisms, independent of cell cycle length.