Intra-mitochondrial proteostasis is directly coupled to alpha-synuclein and Amyloid β 1-42 pathology
Janin Lautenschläger, Sara Wagner-Valladolid, Amberley D. Stephens…·Gabriele S. Kaminski Schierle
This study shows that intra-mitochondrial proteostasis influences alpha-synuclein and Aβ42 aggregation, while mitochondrial stress factors like complex I inhibition do not affect these pathologies.