Drug interaction mapping with proximity dependent enzyme recruiting chimeras
John D. Venable, Ajay Amar Vashisht, Shima Rayatpisheh, James P. Lajiness, Dean P. Phillips, Ansgar Brock
The paper introduces a method to identify small molecule protein targets using engineered biotin ligases and chimeric chemical probes, demonstrating its applicability with various inhibitors.
bioRxiv · Sep 26, 2022 · PreprintMolecular Biology