Author

Ansgar Brock

ORCID 0000-0002-8080-3107Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Ajay Amar Vashisht· 1 shared Charles Y. Cho· 1 shared Cyril H. BenesiD· 1 shared Dean P. PhillipsiD· 1 shared Doug QuackenbushiD· 1 shared Frederick Lo· 1 shared Jacob R. HalingiD· 1 shared James P. Lajiness· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Ajay Amar Vashisht

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2 papers

Recent·Most cited

Remodeling of KRAS interactome induced by clinically relevant RAS inhibitors reveals convergent responses and a KRAS-mediated regulation of directional cell migration

Yang Yang, Charles Y. Cho, Ansgar Brock, Doug Quackenbush, Kaisheng Chen, Frederick Lo, Cyril H. Benes, Jacob R. Haling

This study examines how RAS inhibitors alter the KRAS interactome, revealing shared responses and a role for KRAS in regulating directional cell migration.

bioRxiv · Nov 14, 2025 · PreprintCancer Biology

Drug interaction mapping with proximity dependent enzyme recruiting chimeras

John D. Venable, Ajay Amar Vashisht, Shima Rayatpisheh, James P. Lajiness, Dean P. Phillips, Ansgar Brock

The paper introduces a method to identify small molecule protein targets using engineered biotin ligases and chimeric chemical probes, demonstrating its applicability with various inhibitors.

bioRxiv · Sep 26, 2022 · PreprintMolecular Biology