A sensitive red/far-red photoswitch for controllable gene therapy in mouse models of metabolic diseases
Longliang Qiao, Lingxue Niu, Meiyan Wang, Zhihao Wang, Deqiang Kong, Guiling Yu, Haifeng Ye
This paper develops a red/far-red light-inducible photoswitch system for optogenetic control of gene expression in mice, demonstrating its application in treating metabolic diseases.
Nature Communications · Nov 27, 2024Peer-reviewedSynthetic Biology