Author

Haifeng Ye

East China Normal UniversityORCID 0000-0002-5482-8116Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:gene regulatory network inference· 2 Research Focus:drug response / drug discovery· 1 Research Focus:genome assembly· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Research Focus:protein design· 1

Frequent Co-Authors

Deqiang KongiD· 3 shared Alexandra FischeriD· 1 shared Bodo GrimbacheriD· 1 shared Carsten BaltesiD· 1 shared Dali LiiD· 1 shared Franziska LautenschlägeriD· 1 shared Guiling YuiD· 1 shared Hanah B. Robertson· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersSynthetic Biology

Deqiang KongORCID

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3 papers

Recent·Most cited

A rapid and efficient red-light-activated Cre recombinase system for genome engineering in mammalian cells and transgenic mice

Yang Zhou, Wei Yu, Jianli Yin, Deqiang Kong, Wenjun Li, Xinyi Wang, Yining Yao, Qin Miao Huang, Lei Li, Mengyao Liu, Longliang Qiao, Huiying Li, Junwei Zhao, Tao P. Zhong, Dali Li, , Haifeng Ye

This paper introduces REDMAPCre, a red-light-activated Cre recombinase system that enables rapid and efficient DNA recombination in mammalian cells and mice.

Nucleic Acids Research · Jul 23, 2025Peer-reviewedSynthetic Biology

A sensitive red/far-red photoswitch for controllable gene therapy in mouse models of metabolic diseases

Longliang Qiao, Lingxue Niu, Meiyan Wang, Zhihao Wang, Deqiang Kong, Guiling Yu, Haifeng Ye

This paper develops a red/far-red light-inducible photoswitch system for optogenetic control of gene expression in mice, demonstrating its application in treating metabolic diseases.

Nature Communications · Nov 27, 2024Peer-reviewedSynthetic Biology

Engineering Material Properties of Transcription Factor Condensates to Control Gene Expression in Mammalian Cells and Mice

Alexandra Fischer, Hanah B. Robertson, Deqiang Kong, Merlin M. Grimm, Jakob Grether, Johanna Groth, Carsten Baltes, Manfred Fliegauf, Franziska Lautenschläger, Bodo Grimbacher, Haifeng Ye, Volkhard Helms, Wilfried Weber

This study tunes the material properties of transcription factor condensates to show their impact on gene expression levels in mammalian cells and mice.

Small · Apr 4, 2024Peer-reviewedSynthetic Biology