Author

Lesley A. Sheach

The Francis Crick InstituteORCID 0000-0002-9959-3779Unclaimed ORCID profile · follow to get notified of new preprints

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Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Antonio A. PostigoiD· 1 shared Christophe J. Queval· 1 shared Darren P. EnnisiD· 1 shared Iain A. McNeishiD· 1 shared Ilaria Dalla RosaiD· 1 shared Katherine E. Tyson· 1 shared Michael T. HowelliD· 1 shared Michael WayiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Antonio A. PostigoORCID

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1 paper

Recent·Most cited

Vinorelbine enhances the efficacy of GM-CSF-armed oncolytic vaccinia virus in a preclinical model of ovarian high grade serous carcinoma

Stefania Drymiotou, Christophe J. Queval, Katherine E. Tyson, Lesley A. Sheach, Antonio A. Postigo, Ilaria Dalla Rosa, Darren P. Ennis, Michael T. Howell, Iain A. McNeish, Michael Way

This study identifies vinorelbine as a compound that enhances the efficacy of a GM-CSF-armed oncolytic vaccinia virus in treating ovarian cancer in mice.

bioRxiv · Feb 4, 2025 · PreprintCancer Biology