ProAgio, a Novel Integrin αvβ3 Targeted Cytotoxin, Suppresses Tumor Growth and Reprograms the PDAC Microenvironment
Dhana Sekhar Reddy Bandi, Sujith Sarvesh, Ganji Purnachandra Nagaraju, Harrison Kim, Jeremy B. Foote, Sejong Bae, Karina Jin Yoon, Midhun Malla, Ashiq Masood, Mehmet Akce, Zhi-Ren Liu, Bassel F. El‐Rayes
ProAgio, an integrin αvβ3-targeted cytotoxin, enhances GPH therapy in PDAC by modulating the tumor microenvironment and improving immune responses.
bioRxiv · Jan 16, 2026 · PreprintCancer Biology