Neuromesodermal Progenitors Advance Network Formation of Spinal Neurons and Support Cells in Neural Ribbons In Vitro and Unprotected Survival in a Rat Subacute Contusion Model
Zachary T. Olmsted, Cinzia Stigliano, Annalisa Scimemi, Brandon J. Marzullo, Tatiana Wolfe, Jose Bernardo Cibelli, Philip J. Horner, Janet L. Paluh
The paper develops in vitro neural ribbons from hiPSCs via neuromesodermal progenitors to generate spinal neurons and support cells, showing their survival and function in a rat SCI model.
bioRxiv · Nov 10, 2020 · PreprintNeuroscience