Deletion of RSK2 kinase alleviates age-dependent hypertension
Ramon Jose Ayon, Yves T. Wang, Jaspreet Kalra, Li Jin, Yen‐Lin Chen, Renata Polanowska‐Grabowska, Swapnil K. Sonkusare, Chris Christie, Eric M. Small, Thu H. Le, Avril V. Somlyo
This study shows that deleting RSK2 kinase in aged mice reduces hypertension by improving vascular relaxation and reducing vessel stiffness.
bioRxiv · Mar 12, 2025 · PreprintPhysiology