Author

Nicholas E. Grayson

Centre for Human GeneticsORCID 0000-0002-9998-6783Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:plant (other)· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Organism:virus· 1

Frequent Co-Authors

Ann Sarah WalkeriD· 1 shared Christoph B. MessneriD· 1 shared David BonsalliD· 1 shared Enrica CalvaniiD· 1 shared Floriana Capuano· 1 shared Joseph ClarkeiD· 1 shared Katrina LythgoeiD· 1 shared Klara M. AnkeriD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperGenomics

Ann Sarah WalkerORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Identification and Masking of Artefactual and Misleading Within-Host Variants in Deep-Sequencing SARS-CoV-2 Data

Klara M. Anker, Rosario Evans Pena, Steven A. Kemp, Joseph Clarke, Lele Zhao, David Bonsall, Nicholas E. Grayson, Matthew Bashton, Ann Sarah Walker, Tanya Golubchik, Matthew Hall, Katrina Lythgoe

The paper identifies and masks artefactual variants in SARS-CoV-2 sequencing data to improve the accuracy of within-host diversity and transmission analysis.

Molecular Biology and Evolution · Aug 17, 2026Peer-reviewedGenomics

Occurrence and quantities of DNA modifications across the tree of life

Sreejith J. Varma, Enrica Calvani, Nana‐Maria Grüning, Christoph B. Messner, Nicholas E. Grayson, Floriana Capuano, Michael Mülleder, Markus Ralser

The paper quantifies DNA modifications across diverse organisms and finds they are common in bacteria and higher eukaryotes but rare in yeast and insects.

eLife · Jul 4, 2022Peer-reviewedGenomics