David J. Craik

This paper demonstrates the use of an asparaginyl endopeptidase ligase to efficiently and selectively functionalize P22 virus-like particles with therapeutic receptor targeting domains.

This paper demonstrates the use of bacteriophage P22 virus-like particles as nanoscale protein scaffolds for plant synthetic biology, showing their ability to assemble, encapsulate, and display proteins in Nicotiana benthamiana.

This study evaluates a bacteriophage P22 VLP system for encapsulating bioactive peptides in E. coli, showing it aids purification but does not significantly improve peptide yields.

This study identifies seasonal gene expression changes in wild crown-of-thorns starfish, revealing reproductive and stress-related transcriptional systems linked to summer breeding and oogenesis.

This study shows that captivity causes large, sustained changes in gene expression in crown-of-thorns starfish, affecting oxidative stress, energy metabolism, and intercellular signaling.

This study demonstrates the rational domestication of Nicotiana benthamiana to expand its ability to produce stable therapeutic peptides.