GeneticsbioRxivPreprint
A conditional histone H3.3 mutation in mice orthologous to a driver of paediatric diffuse instrinsic pontine glioma
Jeff R. Mann, Michelle C. W. Tang, Lee H. Wong
This paper introduces a conditional H3.3K27M mutation in mice to model paediatric diffuse intrinsic pontine glioma, showing dwarfism with intact growth hormone signaling.
DOI 10.1101/2022.11.25.518018