Anne Gatewood Hoen

This study compares RNA extraction and preservation protocols for miRNA profiling in infant and toddler stool, finding that RNAlater and Zymo DNA/RNA Shield yield similar high-quality RNA with comparable human miRNA profiles.

CBEA provides a new method for taxonomic enrichment analysis in microbiome data by using a log-ratio formulation to generate sample-specific enrichment scores.

The paper evaluates trait-based taxonomic enrichment methods for human microbiome data, finding they improve disease prediction and interpretability.

The paper proposes a stationary Gaussian graphical model for microbial interaction networks using longitudinal 16S rRNA data and shows it outperforms conventional methods in correlated settings.

The paper introduces a method for selecting Gaussian graphical models using prior knowledge and applies it to metabolomic data, finding that metabolic pathways significantly influence metabolite dependencies.

The paper introduces a zero-inflated latent Ising model to estimate microbial interaction networks, showing it outperforms traditional methods in simulated and real gut microbiome data.