Human Decidual RUNX1 Promotes Angiogenesis and Trophoblast Differentiation by Regulating Extracellular Vesicle Signaling
Jacob R. Beal, Xiangning Song, Athilakshmi Kannan…·Milan K. Bagchi
This study shows that RUNX1 in human decidual cells regulates extracellular vesicle secretion and cargo proteins like ANGPTL2 and IGF2, which promote angiogenesis and trophoblast differentiation during placenta formation.