Milan K. Bagchi

This study identifies HIF2α-regulated extracellular vesicles as mediators of trophoblast communication with endometrial stromal cells, influencing invasion and tissue remodeling during early placental development.

This study shows that loss of Glut1 in mouse uterine cells disrupts trophoblast differentiation and causes gestational diabetes.

This study shows that RUNX1 in human decidual cells regulates extracellular vesicle secretion and cargo proteins like ANGPTL2 and IGF2, which promote angiogenesis and trophoblast differentiation during placenta formation.

This study shows that long-term exposure to a phthalate mixture in mice causes endometrial hyperplasia by enhancing estrogen and beta-catenin signaling pathways.

This study shows that phthalates disrupt estrogenic regulation of HIF2α and EV secretion in human endometrial stromal cells by altering DNA methylation and transcription factor binding.