GenomicsCellPeer-reviewed
Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders
Zinan Zhou, Lovelace J. Luquette, Guanlan Dong…·Christopher A. Walsh
The paper identifies a shared TOP1-mediated mutagenic mechanism in ALS, FTD, and AD through single-cell genomic analysis and experimental validation.
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