Eitan Goodman

The paper identifies pervasive somatic NF1 mutations in oligodendrocyte precursors in NF-1 patients, showing clonal selection and spatial bias, and links CDKN2A loss to tumor progression.

The paper identifies a shared TOP1-mediated mutagenic mechanism in ALS, FTD, and AD through single-cell genomic analysis and experimental validation.

The paper analyzes somatic mutations in cerebellar granule neurons and finds distinct mutation patterns compared to other neuronal types, suggesting links to cancer origins and neurodegeneration.