Author

Allison L. Brichacek

West Virginia UniversityORCID 0000-0003-0115-2535Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Candice M. BrowniD· 3 shared Divine C. NwaforiD· 3 shared Catheryne A. GambilliD· 2 shared Elizabeth B. Engler-ChiurazziiD· 2 shared José Luís MillániD· 2 shared Sreeparna ChakrabortyiD· 2 shared Stanley Anthony BenkoviciD· 2 shared Sujung JuniD· 2 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Candice M. BrownORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 25, 2021

Brain endothelial cell tissue-nonspecific alkaline phosphatase (TNAP) activity promotes maintenance of barrier integrity via the ROCK pathway

Divine C. Nwafor, Allison L. Brichacek, Wei Wang…·Candice M. Brown

This study shows that TNAP activity in brain endothelial cells maintains barrier integrity via the ROCK pathway, and its inhibition leads to barrier dysfunction.

4 citations

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintApr 29, 2020

Experimental Stroke Induces Chronic Gut Dysbiosis and Neuroinflammation in Male Mice

Allison L. Brichacek, Divine C. Nwafor, Stanley Anthony Benkovic…·Candice M. Brown

This study shows that experimental stroke in male mice leads to chronic gut dysbiosis and neuroinflammation lasting up to one month.

8 citations

mousebulk RNA-seq

𝕏 PostBluesky

NeuroscienceBrain Behavior and ImmunityPeer-reviewedNov 25, 2019

Loss of tissue non-specific alkaline phosphatase (TNAP) enzyme activity in cerebral microvessels is coupled to persistent neuroinflammation and behavioral deficits in late sepsis

Divine C. Nwafor, Sreeparna Chakraborty, Allison L. Brichacek…·Candice M. Brown

This study shows that reduced TNAP enzyme activity in cerebral microvessels during late sepsis is linked to neuroinflammation and behavioral changes like anti-nociception.

19 citations

mouseexperimental assay

𝕏 PostBluesky