Sebastian Guenther

FoXSight identifies weak binding events in crystallographic fragment screening by detecting target-specific density features in noisy electron density maps.

This study shows that temperatures above 37°C increase hypermucoviscosity and virulence in a convergent Klebsiella pneumoniae strain, potentially due to plasmid-encoded factors and temperature-dependent regulatory changes.

This study identifies unique pathogenic markers in Klebsiella pneumoniae through multi-omics analysis, suggesting potential novel antimicrobial targets.

The paper characterizes the genomic diversity of multi-drug resistant Escherichia coli in wastewater, finding high genetic variation and resistance/virulence genes.