Karsten Becker

The paper identifies HERC4 as a regulator of ROS-induced DNA damage during bacterial and viral-bacterial infections, showing its role in DNA repair and potential as a therapeutic target.

This study shows that SKP2 limits autophagy during S. aureus infection by stabilizing and translocating to the cytoplasm, reducing LC3-II levels and intracellular bacterial survival.

This study investigates in-host evolution of Klebsiella pneumoniae sequence type 147 isolates, revealing microevolution from classic to convergent pathotype through plasmid acquisition and capsular changes affecting virulence and morphology.

This paper evaluates recent improvements in Oxford Nanopore sequencing for bacterial genomic surveillance, showing that new software tools significantly enhance accuracy and reproducibility.

This study shows that temperatures above 37°C increase hypermucoviscosity and virulence in a convergent Klebsiella pneumoniae strain, potentially due to plasmid-encoded factors and temperature-dependent regulatory changes.