Author

Sarah Giles

Scripps Research InstituteORCID 0000-0003-0177-2654Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:database / resource· 1

Frequent Co-Authors

Kevin EadeiD· 4 shared Martin FriedlanderiD· 3 shared Roberto BonelliiD· 2 shared Sarah R. Harkins-PerryiD· 2 shared Alberto Docampo-SearaiD· 1 shared Andrew E. TimmsiD· 1 shared Ava MaeyamaiD· 1 shared Ayumi Usui‐OuchiiD· 1 shared

Activity by Year

2022-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersDevelopmental Biology

Kevin EadeORCID

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4 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintJul 30, 2026

Encapsulated cell technology delivers ciliary neurotrophic factor to promote JAK/STAT-dependent photoreceptor survival in retinal degeneration

Yasuaki Iwama, Leia Laughlin, Sarah R. Harkins-Perry…·Kevin Eade

This study shows NT-501 reduces photoreceptor death in retinal models by CNTF-dependent JAK/STAT3 activation, establishing an optimal dose range for efficacy.

DOI 10.64898/2026.07.27.740168

humanproteomics

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Developmental BiologybioRxivPreprintJul 20, 2026

An early CYP26A1/CRYAA progenitor-glial domain marks the presumptive macular region during human retinal development

Qian Yang, Alberto Docampo-Seara, Michael Barry Powner…·Marcus Fruttiger

The paper identifies a CYP26A1/CRYAA progenitor-glial domain in the human retina that marks the presumptive macula and links it to regional gliogenic maturation and specialized Muller glial populations.

DOI 10.64898/2026.07.17.738962

humanscRNA-seq

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NeuroscienceNature NeurosciencePeer-reviewedJun 19, 2026

Erucamide regulates retinal neurovascular crosstalk

Guoqin Wei, Shreyosree Chatterjee, Qinglin Yang…·Martin Friedlander

This study identifies erucamide as a key regulator of retinal neurovascular crosstalk, showing its role in stabilizing retinal degeneration through TMEM19-mediated activation of myeloid cells.

1 citation

mousemetabolomics

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Developmental BiologyDevelopmental CellPeer-reviewedMar 1, 2022

Multi-omic Analysis of Developing Human Retina and Organoids Reveals Cell-Specific Cis-Regulatory Elements and Mechanisms of Non-Coding Genetic Disease Risk.

Eric D. Thomas, Andrew E. Timms, Sarah Giles…·Timothy J. Cherry

The paper identifies cell-class-specific cis-regulatory elements in human retina and organoids, showing their correlation and function in development and disease.

85 citationstop 2%

humanscATAC-seq

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