Martin Friedlander

This study shows NT-501 reduces photoreceptor death in retinal models by CNTF-dependent JAK/STAT3 activation, establishing an optimal dose range for efficacy.

This study identifies erucamide as a key regulator of retinal neurovascular crosstalk, showing its role in stabilizing retinal degeneration through TMEM19-mediated activation of myeloid cells.

The paper investigates retinal spheroid layer formation by analyzing Rax::GFP-positive retinal progenitor cells, revealing sequential WNT signaling and environmental factors in retinal development.

The paper shows that depleting the gut microbiome in aged mice rejuvenates the brain by improving vascular density, myelination, neurogenesis, and reducing inflammation.

This study quantifies vascular tortuosity in the OIR model, showing it correlates with disease activity and responds to treatment with aflibercept.

The paper identifies cell-class-specific cis-regulatory elements in human retina and organoids, showing their correlation and function in development and disease.