Author

Cuilee Sha

National Institutes of HealthORCID 0000-0003-0188-2802Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Brian P. BrooksiD· 1 shared Charles DeYoungiD· 1 shared David R. AdamsiD· 1 shared Diksha Shukla· 1 shared Jonathan Hale ZippiniD· 1 shared Joseph Bonica· 1 shared Matthew B. Boxer· 1 shared Matthew D. HalliD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Brian P. BrooksORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintOct 13, 2025

Ampyrone (4-Aminoantipyrine) is a Direct Agonist of Human Tyrosinase and Potential Therapeutic for Oculocutaneous Albinism and Disorders of Hypopigmentation.

Monika B. Dolinska, Yuhong Wang, Nathan P. Coussens…·Brian P. Brooks

The paper identifies ampyrone as a direct activator of human tyrosinase, showing increased catalytic activity and melanin synthesis in melanocytes and skin cultures, suggesting potential therapeutic use for hypopigmentation disorders.

1 citation

humanexperimental assay

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