Clinical Trial and Ontology-Derived Positive and Negative Benchmark Datasets for Drug Repurposing Across Rare Diseases
Babak Ravandi, William R. Mowrey, Ayan Chatterjee…·Gabriel Tarrason Risa
The paper introduces two benchmark datasets for drug repurposing across rare diseases: a positive dataset from clinical trials and a negative dataset from disease ontologies, enabling evaluation of computational models for disease-drug associations.