Author

Suzanne Gaye Orchard

Monash UniversityORCID 0000-0003-0211-3183Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:whole-exome sequencing· 2 Research Focus:polygenic risk· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Anne M. MurrayiD· 3 shared Jane M. TilleriD· 3 shared John J. McNeiliD· 3 shared Moeen RiaziD· 3 shared Paul A LacazeiD· 3 shared Robert SebraiD· 3 shared Robyn L. WoodsiD· 3 shared Bryony A. ThompsoniD· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Anne M. MurrayORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicineCancersPeer-reviewedJul 14, 2021

Genomic risk prediction for breast cancer in older women

Paul A Lacaze, Andrew Bakshi, Moeen Riaz…·John J. McNeil

This study evaluates a polygenic risk score for breast cancer in women aged 70 and older, finding it improves risk prediction beyond conventional factors.

8 citations

humanwhole-exome sequencing

𝕏 PostBluesky

Genetic & Genomic MedicineAging CellPeer-reviewedMay 26, 2021

Effect of APOE and a polygenic risk score on incident dementia and cognitive decline in a healthy older population

Moeen Riaz, Aamira J. Huq, Joanne L. Ryan…·Paul A Lacaze

This study examines the effect of APOE genotypes and polygenic risk scores on dementia and cognitive decline in a longitudinal cohort of healthy older individuals, finding increased risks for APOE ε4 carriers and high PRS tertiles.

44 citationstop 3%

humanstatistical model

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintOct 22, 2019

Resilience to dominant genetic disease in the healthy elderly

Paul A Lacaze, Robert Sebra, Moeen Riaz…·Eric Schadt

The paper screens healthy elderly individuals to identify those resilient to genetic diseases despite high genetic risk, finding 141 individuals without associated disease despite pathogenic variants.

DOI 10.1101/19006932

humanwhole-exome sequencing

𝕏 PostBluesky