Author

Kirby D. Johnson

University of Wisconsin–MadisonORCID 0000-0003-0236-7482Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1

Frequent Co-Authors

Emery H. BresnickiD· 2 shared Daniel J. ConniD· 1 shared Shan LuiD· 1 shared Shuyang Chen· 1 shared Sündüz KeleşiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersGenomics

Emery H. BresnickORCID

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2 papers

Recent·Most cited

MLG: Multilayer graph clustering for multi-condition scRNA-seq data

Shan Lu, Daniel J. Conn, Shuyang Chen, Kirby D. Johnson, Emery H. Bresnick, Sündüz Keleş

MLG improves clustering accuracy in multi-condition scRNA-seq data by integrating multiple dimensionality reduction methods.

Nucleic Acids Research · Sep 21, 2021Peer-reviewedGenomics

GATA2 deficiency during embryogenesis elevates Interferon Regulatory Factor-8 to subvert a progenitor cell differentiation program

Kirby D. Johnson, Emery H. Bresnick

The paper shows that GATA2 deficiency during embryogenesis leads to elevated IRF8, which disrupts progenitor cell differentiation by altering the balance of myelo-erythroid progeny.

bioRxiv · Jan 29, 2021 · PreprintDevelopmental Biology