Emery H. Bresnick

This paper introduces BasCoD, a framework for selecting optimal backgrounds in contrastive dimension reduction, improving contrast and interpretability in single-cell data.

The paper identifies epigenetic and signaling factors that regulate BBB formation and maintenance in CNS endothelial cells.

MLG improves clustering accuracy in multi-condition scRNA-seq data by integrating multiple dimensionality reduction methods.

The paper shows that GATA2 deficiency during embryogenesis leads to elevated IRF8, which disrupts progenitor cell differentiation by altering the balance of myelo-erythroid progeny.

PRAM improves transcript discovery from RNA-seq data by combining datasets in a single step, outperforming two-step methods and identifying new transcripts in human and mouse data.