Author

Peter Watson

Cardiff UniversityORCID 0000-0003-0250-7852Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:mechanistic / dynamical model· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

D. Dafydd JonesiD· 2 shared Danoo VitsupakorniD· 2 shared Rochelle D. AhmediD· 2 shared Athena ZittiiD· 1 shared Kai A. PawsoniD· 1 shared Karma M. AlbalawiiD· 1 shared Kieran D HartwelliD· 1 shared Oliver Kieran CastelliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

D. Dafydd JonesORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJan 8, 2025

Molecular dynamics guided engineering of Aequorea victoria Green Fluorescent Protein chromophore interactions generates a brighter variant with improved photobleaching resistance

Rochelle D. Ahmed, William David Jamieson, Danoo Vitsupakorn…·D. Dafydd Jones

The paper engineers a brighter and more photostable variant of avGFP by modifying chromophore interactions, resulting in improved fluorescence and resistance to photobleaching.

DOI 10.1101/2025.01.08.631926

protein structuremechanistic / dynamical model

𝕏 PostBluesky

BiochemistryChemical SciencePeer-reviewedJan 1, 2025

Chromophore charge-state switching through copper-dependent homodimerisation of an engineered green fluorescent protein.

Rochelle D. Ahmed, Danoo Vitsupakorn, Kieran D Hartwell…·D. Dafydd Jones

This paper engineers a green fluorescent protein that changes its chromophore charge state through copper-dependent homodimerisation, resulting in a 30-fold fluorescence emission ratio change.

1 citation

protein structurefluorescence / live-cell microscopy

𝕏 PostBluesky