Molecular BiologybioRxiv
Native molecule sequencing by nano-ID reveals synthesis and stability of RNA isoforms
Kerstin C. Maier, Saskia Gressel, Patrick Cramer, Björn Schwalb
The paper introduces nano-ID, a method using nanopore sequencing and machine learning to study RNA isoform synthesis and stability, revealing differences in metabolism between individual isoforms and gene-level estimates.
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