Author

Zhu Zhu

Brigham and Women's HospitalORCID 0000-0003-0274-8007Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:CITE-seq· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

María Gutiérrez‐ArcelusiD· 3 shared Qian XiaoiD· 3 shared Adam T. Chicoine· 2 shared Alessandra NervianiiD· 2 shared Ami Ben‐Artzi· 2 shared Amit LakhanpaliD· 2 shared Andrew C. CordleiD· 2 shared Andrew D. FileriD· 2 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

María Gutiérrez‐ArcelusORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicineNature CommunicationsPeer-reviewedOct 23, 2026

A multi-omics resource of B cell activation reveals genetic mechanisms for immune-mediated diseases

Vitor R. C. Aguiar, Marcella E. Franco, Nada Abdel Aziz…·María Gutiérrez‐Arcelus

This study profiles B cell activation states using multi-omics data to identify genetic mechanisms underlying immune-mediated diseases.

DOI 10.1038/s41467-026-78656-w

𝕏 PostBluesky

ImmunologyNaturePeer-reviewedFeb 6, 2025

Granzyme K drives a newly-intentified pathway of complement activation

C. A. Donado, Erin Theisen, Fan Zhang…·Michael B. Brenner

This study identifies granzyme K as a driver of a novel complement activation pathway independent of classical, lectin, or alternative pathways.

154 citationstop 1%

humanproteomics

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GenomicsbioRxivPreprintFeb 25, 2022

Cellular deconstruction of inflamed synovium defines diverse inflammatory phenotypes in rheumatoid arthritis

Fan Zhang, Anna Helena Jonsson, Aparna Nathan…·Zhu Zhu

The paper deconstructs RA synovium using single-cell data to identify six cell type abundance phenotypes associated with distinct inflammatory states.

30 citations

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